CoA synthase regulates mitotic fidelity via CBP-mediated acetylation

The temporal activation of kinases and timely ubiquitin-mediated degradation is central to faithful mitosis. Here we present evidence that acetylation controlled by Coenzyme A synthase (COASY) and acetyltransferase CBP constitutes a novel mechanism that ensures faithful mitosis. We found that COASY...

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Detalles Bibliográficos
Autores principales: Lin, Chao-Chieh, Kitagawa, Mayumi, Tang, Xiaohu, Hou, Ming-Hsin, Wu, Jianli, Qu, Dan Chen, Srinivas, Vinayaka, Liu, Xiaojing, Thompson, J. Will, Mathey-Prevot, Bernard, Yao, Tso-Pang, Lee, Sang Hyun, Chi, Jen-Tsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847545/
https://www.ncbi.nlm.nih.gov/pubmed/29531224
http://dx.doi.org/10.1038/s41467-018-03422-6

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