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Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer

Ovarian cancer (OC) is most lethal malignancy among all gynecological cancer. Large bodies of evidences suggest that mitochondrial-derived ROS play a critical role in the development and progression of OC. Paraoxonase 2 (PON2) is a membrane-associated lactonase with anti-oxidant properties. PON2 def...

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Detalles Bibliográficos
Autores principales:	Devarajan, Asokan, Su, Feng, Grijalva, Victor, Yalamanchi, Meghna, Yalamanchi, Ashna, Gao, Feng, Trost, Hannah, Nwokedi, Josephine, Farias-Eisner, Gina, Farias-Eisner, Robin, Fogelman, Alan M., Reddy, Srinivasa T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847560/ https://www.ncbi.nlm.nih.gov/pubmed/29531225 http://dx.doi.org/10.1038/s41419-018-0395-2

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