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Senescence promotes in vivo reprogramming through p16(INK) (4a) and IL‐6

Cellular senescence is a damage response aimed to orchestrate tissue repair. We have recently reported that cellular senescence, through the paracrine release of interleukin‐6 (IL6) and other soluble factors, strongly favors cellular reprogramming by Oct4, Sox2, Klf4, and c‐Myc (OSKM) in nonsenescen...

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Detalles Bibliográficos
Autores principales:	Mosteiro, Lluc, Pantoja, Cristina, de Martino, Alba, Serrano, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847859/ https://www.ncbi.nlm.nih.gov/pubmed/29280266 http://dx.doi.org/10.1111/acel.12711

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