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Survey of Candidate Genes for Maize Resistance to Infection by Aspergillus flavus and/or Aflatoxin Contamination

Many projects have identified candidate genes for resistance to aflatoxin accumulation or Aspergillus flavus infection and growth in maize using genetic mapping, genomics, transcriptomics and/or proteomics studies. However, only a small percentage of these candidates have been validated in field con...

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Autores principales: Hawkins, Leigh K., Warburton, Marilyn L., Tang, Juliet D., Tomashek, John, Alves Oliveira, Dafne, Ogunola, Oluwaseun F., Smith, J. Spencer, Williams, W. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848162/
https://www.ncbi.nlm.nih.gov/pubmed/29385107
http://dx.doi.org/10.3390/toxins10020061
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author Hawkins, Leigh K.
Warburton, Marilyn L.
Tang, Juliet D.
Tomashek, John
Alves Oliveira, Dafne
Ogunola, Oluwaseun F.
Smith, J. Spencer
Williams, W. Paul
author_facet Hawkins, Leigh K.
Warburton, Marilyn L.
Tang, Juliet D.
Tomashek, John
Alves Oliveira, Dafne
Ogunola, Oluwaseun F.
Smith, J. Spencer
Williams, W. Paul
author_sort Hawkins, Leigh K.
collection PubMed
description Many projects have identified candidate genes for resistance to aflatoxin accumulation or Aspergillus flavus infection and growth in maize using genetic mapping, genomics, transcriptomics and/or proteomics studies. However, only a small percentage of these candidates have been validated in field conditions, and their relative contribution to resistance, if any, is unknown. This study presents a consolidated list of candidate genes identified in past studies or in-house studies, with descriptive data including genetic location, gene annotation, known protein identifiers, and associated pathway information, if known. A candidate gene pipeline to test the phenotypic effect of any maize DNA sequence on aflatoxin accumulation resistance was used in this study to determine any measurable effect on polymorphisms within or linked to the candidate gene sequences, and the results are published here.
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spelling pubmed-58481622018-03-14 Survey of Candidate Genes for Maize Resistance to Infection by Aspergillus flavus and/or Aflatoxin Contamination Hawkins, Leigh K. Warburton, Marilyn L. Tang, Juliet D. Tomashek, John Alves Oliveira, Dafne Ogunola, Oluwaseun F. Smith, J. Spencer Williams, W. Paul Toxins (Basel) Article Many projects have identified candidate genes for resistance to aflatoxin accumulation or Aspergillus flavus infection and growth in maize using genetic mapping, genomics, transcriptomics and/or proteomics studies. However, only a small percentage of these candidates have been validated in field conditions, and their relative contribution to resistance, if any, is unknown. This study presents a consolidated list of candidate genes identified in past studies or in-house studies, with descriptive data including genetic location, gene annotation, known protein identifiers, and associated pathway information, if known. A candidate gene pipeline to test the phenotypic effect of any maize DNA sequence on aflatoxin accumulation resistance was used in this study to determine any measurable effect on polymorphisms within or linked to the candidate gene sequences, and the results are published here. MDPI 2018-01-31 /pmc/articles/PMC5848162/ /pubmed/29385107 http://dx.doi.org/10.3390/toxins10020061 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hawkins, Leigh K.
Warburton, Marilyn L.
Tang, Juliet D.
Tomashek, John
Alves Oliveira, Dafne
Ogunola, Oluwaseun F.
Smith, J. Spencer
Williams, W. Paul
Survey of Candidate Genes for Maize Resistance to Infection by Aspergillus flavus and/or Aflatoxin Contamination
title Survey of Candidate Genes for Maize Resistance to Infection by Aspergillus flavus and/or Aflatoxin Contamination
title_full Survey of Candidate Genes for Maize Resistance to Infection by Aspergillus flavus and/or Aflatoxin Contamination
title_fullStr Survey of Candidate Genes for Maize Resistance to Infection by Aspergillus flavus and/or Aflatoxin Contamination
title_full_unstemmed Survey of Candidate Genes for Maize Resistance to Infection by Aspergillus flavus and/or Aflatoxin Contamination
title_short Survey of Candidate Genes for Maize Resistance to Infection by Aspergillus flavus and/or Aflatoxin Contamination
title_sort survey of candidate genes for maize resistance to infection by aspergillus flavus and/or aflatoxin contamination
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848162/
https://www.ncbi.nlm.nih.gov/pubmed/29385107
http://dx.doi.org/10.3390/toxins10020061
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