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Strategies to Improve the Clinical Utility of Saporin-Based Targeted Toxins

Plant Ribosome-inactivating proteins (RIPs) including the type I RIP Saporin have been used for the construction of Immunotoxins (ITxs) obtained via chemical conjugation of the toxic domain to whole antibodies or by generating genetic fusions to antibody fragments/targeting domains able to direct th...

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Detalles Bibliográficos
Autores principales:	Giansanti, Francesco, Flavell, David J., Angelucci, Francesco, Fabbrini, Maria Serena, Ippoliti, Rodolfo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848183/ https://www.ncbi.nlm.nih.gov/pubmed/29438358 http://dx.doi.org/10.3390/toxins10020082

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