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Optimal Fixation Conditions and DNA Extraction Methods for MLPA Analysis on FFPE Tissue-Derived DNA

Objectives: Molecular genetic analysis of formalin-fixed, paraffin-embedded (FFPE) tissues is of great importance both for research and diagnostics. Multiplex ligation-dependent probe amplification (MLPA) is a widely used technique for gene copy number determination, and it has been successfully use...

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Detalles Bibliográficos
Autores principales: Atanesyan, Lilit, Steenkamer, Maryvonne J., Horstman, Anja, Moelans, Cathy B., Schouten, Jan P., Savola, Suvi P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848216/
https://www.ncbi.nlm.nih.gov/pubmed/28122725
http://dx.doi.org/10.1093/ajcp/aqw205