The use of tea tree oil in treating blepharitis and meibomian gland dysfunction

INTRODUCTION: Blepharitis and meibomian gland dysfunction are chronic inflammatory conditions with overlapping pathophysiology and symptomatology. Both microbial infection and seborrhea contribute to the pathophysiology and both may benefit from treatment with tea tree oil (TTO). We evaluated the therapeutic effect of eyelids scrubbing with TTO in a group of patients with lid margin disease. MATERIALS AND METHODS: Forty patients were recruited. Half of them received lid scrubbing with a TTO formula (Naviblef™) and the other half was treated by massage and cleansing. The effect on ocular surface symptoms, tear film stability, and lid signs was evaluated. RESULTS: All patients receiving TTO improved in symptoms, signs, and tear film stability, and the improvement was statistically significant at P < 0.001. Only five patients in massage group showed improvement. The changes in massage group were not statistically significant at P < 0.001. TTO is very effective in relieving symptoms and improving tear film stability and lid signs.