The D113N mutation in the RING E3 ubiquitin protein ligase gene is not associated with ex vivo susceptibility to common anti-malarial drugs in African Plasmodium falciparum isolates

BACKGROUND: Plasmodium falciparum resistance to artemisinin-based combination therapy has emerged and spread in Southeast Asia. In areas where artemisinin resistance is emerging, the efficacy of combination is now based on partner drugs. In this context, the identification of novel markers of resist...

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Detalles Bibliográficos
Autores principales: Gendrot, Mathieu, Foguim, Francis Tsombeng, Robert, Marie Gladys, Amalvict, Rémy, Mosnier, Joel, Benoit, Nicolas, Madamet, Marylin, Pradines, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848522/
https://www.ncbi.nlm.nih.gov/pubmed/29530046
http://dx.doi.org/10.1186/s12936-018-2252-2

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