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Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN

BACKGROUND: Diabetic patients have a higher risk factor for colorectal cancer (CRC) metastasis. Stearoyl-CoA desaturase 1 (SCD1), the main enzyme responsible for producing monounsaturated fatty acids(MUFA) from saturated fatty acids, is frequently deregulated in both diabetes and CRC. The function a...

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Detalles Bibliográficos
Autores principales:	Ran, Hui, Zhu, Yemin, Deng, Ruyuan, Zhang, Qi, Liu, Xisheng, Feng, Ming, Zhong, Jie, Lin, Shuhai, Tong, Xuemei, Su, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848567/ https://www.ncbi.nlm.nih.gov/pubmed/29530061 http://dx.doi.org/10.1186/s13046-018-0711-9

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