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Deregulated microRNA and mRNA expression profiles in the peripheral blood of patients with Marfan syndrome

BACKGROUND: MicroRNAs (miRNAs) are small RNAs regulating gene expression post-transcriptionally. While acquired changes of miRNA and mRNA profiles in cancer have been extensively studied, little is known about expression changes of circulating miRNAs and messenger RNAs (mRNA) in monogenic constituti...

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Detalles Bibliográficos
Autores principales: Abu-Halima, Masood, Kahraman, Mustafa, Henn, Dominic, Rädle-Hurst, Tanja, Keller, Andreas, Abdul-Khaliq, Hashim, Meese, Eckart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848586/
https://www.ncbi.nlm.nih.gov/pubmed/29530068
http://dx.doi.org/10.1186/s12967-018-1429-3