3′ UTR lengthening as a novel mechanism in regulating cellular senescence

Cellular senescence has been viewed as a tumor suppression mechanism and also as a contributor to individual aging. Widespread shortening of 3′ untranslated regions (3′ UTRs) in messenger RNAs (mRNAs) by alternative polyadenylation (APA) has recently been discovered in cancer cells. However, the rol...

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Detalles Bibliográficos
Autores principales: Chen, Meng, Lyu, Guoliang, Han, Miao, Nie, Hongbo, Shen, Ting, Chen, Wei, Niu, Yichi, Song, Yifan, Li, Xueping, Li, Huan, Chen, Xinyu, Wang, Ziyue, Xia, Zheng, Li, Wei, Tian, Xiao-Li, Ding, Chen, Gu, Jun, Zheng, Yufang, Liu, Xinhua, Hu, Jinfeng, Wei, Gang, Tao, Wei, Ni, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848608/
https://www.ncbi.nlm.nih.gov/pubmed/29440281
http://dx.doi.org/10.1101/gr.224451.117

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