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Enhancer RNA profiling predicts transcription factor activity

Transcription factors (TFs) exert their regulatory influence through the binding of enhancers, resulting in coordination of gene expression programs. Active enhancers are often characterized by the presence of short, unstable transcripts termed enhancer RNAs (eRNAs). While their function remains unc...

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Detalles Bibliográficos
Autores principales: Azofeifa, Joseph G., Allen, Mary A., Hendrix, Josephina R., Read, Timothy, Rubin, Jonathan D., Dowell, Robin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848612/
https://www.ncbi.nlm.nih.gov/pubmed/29449408
http://dx.doi.org/10.1101/gr.225755.117