Targeted deletion of a 170-kb cluster of LINE-1 repeats and implications for regional control

Approximately half the mammalian genome is composed of repetitive sequences, and accumulating evidence suggests that some may have an impact on genome function. Here, we characterized a large array class of repeats of long-interspersed elements (LINE-1). Although widely distributed in mammals, locat...

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Detalles Bibliográficos
Autores principales: Soares, Miguel L., Edwards, Carol A., Dearden, Frances L., Ferrón, Sacri R., Curran, Scott, Corish, Jennifer A., Rancourt, Rebecca C., Allen, Sarah E., Charalambous, Marika, Ferguson-Smith, Malcolm A., Rens, Willem, Adams, David J., Ferguson-Smith, Anne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848613/
https://www.ncbi.nlm.nih.gov/pubmed/29367313
http://dx.doi.org/10.1101/gr.221366.117

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