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Discovery of a Novel Molecule that Regulates Tumor Growth and Metastasis

The heparan sulfate proteoglycan, Glypican-1 (GPC1), significantly impacts the growth of pancreatic cancer cells in vivo and markedly attenuates tumor angiogenesis and metastasis in athymic mice. Interestingly, both cancer cell–derived and host-derived GPC1 play an important role in tumor developmen...

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Detalles Bibliográficos
Autores principales:	Whipple, Chery A., Lander, Arthur D., Korc, Murray
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	TheScientificWorldJOURNAL 2008
Materias:	Directions in Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848622/ https://www.ncbi.nlm.nih.gov/pubmed/19082421 http://dx.doi.org/10.1100/tsw.2008.152

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