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Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee

Humans experience higher rates of age-associated diseases than our closest living evolutionary relatives, chimpanzees. Environmental factors can explain many of these increases in disease risk, but species-specific genetic changes can also play a role. Alleles that confer increased disease susceptib...

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Detalles Bibliográficos
Autores principales:	Pizzollo, Jason, Nielsen, William J, Shibata, Yoichiro, Safi, Alexias, Crawford, Gregory E, Wray, Gregory A, Babbitt, Courtney C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848805/ https://www.ncbi.nlm.nih.gov/pubmed/29608722 http://dx.doi.org/10.1093/gbe/evy041

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