TopUp SERS Substrates with Integrated Internal Standard

Surface-enhanced Raman spectroscopy (SERS) is known as a molecular-specific and highly sensitive method. In order to enable the routine application of SERS, powerful SERS substrates are of great importance. Within this manuscript, a TopUp SERS substrate is introduced which is fabricated by a top-dow...

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Autores principales: Patze, Sophie, Huebner, Uwe, Weber, Karina, Cialla-May, Dana, Popp, Juergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849022/
https://www.ncbi.nlm.nih.gov/pubmed/29495266
http://dx.doi.org/10.3390/ma11020325
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author Patze, Sophie
Huebner, Uwe
Weber, Karina
Cialla-May, Dana
Popp, Juergen
author_facet Patze, Sophie
Huebner, Uwe
Weber, Karina
Cialla-May, Dana
Popp, Juergen
author_sort Patze, Sophie
collection PubMed
description Surface-enhanced Raman spectroscopy (SERS) is known as a molecular-specific and highly sensitive method. In order to enable the routine application of SERS, powerful SERS substrates are of great importance. Within this manuscript, a TopUp SERS substrate is introduced which is fabricated by a top-down process based on microstructuring as well as a bottom-up generation of silver nanostructures. The Raman signal of the support material acts as an internal standard in order to improve the quantification capabilities. The analyte molecule coverage of sulfamethoxazole on the surface of the nanostructures is characterized by the SERS signal evolution fitted by a Langmuir–Freundlich isotherm.
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spelling pubmed-58490222018-03-14 TopUp SERS Substrates with Integrated Internal Standard Patze, Sophie Huebner, Uwe Weber, Karina Cialla-May, Dana Popp, Juergen Materials (Basel) Article Surface-enhanced Raman spectroscopy (SERS) is known as a molecular-specific and highly sensitive method. In order to enable the routine application of SERS, powerful SERS substrates are of great importance. Within this manuscript, a TopUp SERS substrate is introduced which is fabricated by a top-down process based on microstructuring as well as a bottom-up generation of silver nanostructures. The Raman signal of the support material acts as an internal standard in order to improve the quantification capabilities. The analyte molecule coverage of sulfamethoxazole on the surface of the nanostructures is characterized by the SERS signal evolution fitted by a Langmuir–Freundlich isotherm. MDPI 2018-02-24 /pmc/articles/PMC5849022/ /pubmed/29495266 http://dx.doi.org/10.3390/ma11020325 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Patze, Sophie
Huebner, Uwe
Weber, Karina
Cialla-May, Dana
Popp, Juergen
TopUp SERS Substrates with Integrated Internal Standard
title TopUp SERS Substrates with Integrated Internal Standard
title_full TopUp SERS Substrates with Integrated Internal Standard
title_fullStr TopUp SERS Substrates with Integrated Internal Standard
title_full_unstemmed TopUp SERS Substrates with Integrated Internal Standard
title_short TopUp SERS Substrates with Integrated Internal Standard
title_sort topup sers substrates with integrated internal standard
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849022/
https://www.ncbi.nlm.nih.gov/pubmed/29495266
http://dx.doi.org/10.3390/ma11020325
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