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Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis

Glucose-6-phosphate dehydrogenase (G6PD) is a housekeeping enzyme involved in the pentose phosphate shunt for producing nicotinamide adenine dinucleotide phosphate (NADPH). Severe G6PD deficiency leads to embryonic lethality, but the underlying mechanism is unclear. In the current study, the effects...

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Detalles Bibliográficos
Autores principales:	Wu, Yi-Hsuan, Lee, Ying-Hsuan, Shih, Hung-Yu, Chen, Shih-Hsiang, Cheng, Yi-Chuan, Tsun-Yee Chiu, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849038/ https://www.ncbi.nlm.nih.gov/pubmed/29317613 http://dx.doi.org/10.1038/s41419-017-0005-8

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