Sputum or blood eosinophil association with clinical measures of COPD severity in the SPIROMICS cohort

BACKGROUND: Eosinophils in blood and sputum in chronic obstructive pulmonary disease (COPD) have been associated with more frequent exacerbations, lower lung function, and corticosteroid responsiveness. We hypothesized increased eosinophils are associated with a severe COPD phenotype, including exac...

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Detalles Bibliográficos
Autores principales: Hastie, AT, Martinez, FJ, Curtis, JL, Doerschuk, CM, Hansel, NN, Christenson, S, Putcha, N, Ortega, VE, Li, X, Barr, RG, Carretta, EE, Couper, DJ, Cooper, CB, Hoffman, EA, Kanner, RE, Kleerup, E, O’Neal, WK, Paine, R, Peters, SP, Alexis, NE, Woodruff, PG, Han, MK, Meyers, DA, Bleecker, ER
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849066/
https://www.ncbi.nlm.nih.gov/pubmed/29146301
http://dx.doi.org/10.1016/S2213-2600(17)30432-0

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