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Chemoenzymatic synthesis of heparan sulfate and heparin oligosaccharides and NMR analysis: paving the way to a diverse library for glycobiologists
Heparan sulfate (HS) is a member of the glycosaminoglycans (GAG) family that plays essential roles in biological processes from animal sources. Heparin, a highly sulfated form of HS, is widely used as anticoagulant drug worldwide. The high diversity and complexity of HS and heparin represent a roadb...
Autores principales: | Zhang, Xing, Pagadala, Vijayakanth, Jester, Hannah M., Lim, Andrew M., Pham, Truong Quang, Goulas, Anna Marie P., Liu, Jian, Linhardt, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849142/ https://www.ncbi.nlm.nih.gov/pubmed/29568440 http://dx.doi.org/10.1039/c7sc03541a |
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