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Nanomolar small-molecule detection using a genetically encoded (129)Xe NMR contrast agent

Genetically encoded magnetic resonance imaging (MRI) contrast agents enable non-invasive detection of specific biomarkers in vivo. Here, we employed the hyper-CEST (129)Xe NMR technique to quantify maltose (32 nM to 1 mM) through its modulation of conformational change and xenon exchange in maltose...

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Detalles Bibliográficos
Autores principales:	Roose, B. W., Zemerov, S. D., Dmochowski, I. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849143/ https://www.ncbi.nlm.nih.gov/pubmed/29568427 http://dx.doi.org/10.1039/c7sc03601a

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