TRPM8 and RAAS-mediated hypertension is critical for cold-induced immunosuppression in mice

Mechanisms underlying cold-induced immunosuppression remain unclear. Here we found that cold exposure leads to transient receptor potential melastatin 8 (TRPM8)-dependent, renin–angiotensin–aldosterone system (RAAS)-mediated hypertension, which subsequently induces small molecule and fluid extravasa...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Hao, Huang, Hsuan-Shun, Sun, Der-Shan, Lee, Chung-Jen, Lien, Te-Sheng, Chang, Hsin-Hou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849173/
https://www.ncbi.nlm.nih.gov/pubmed/29560109
http://dx.doi.org/10.18632/oncotarget.24356

Ejemplares similares

Ejemplares similares