Hypoxic-induced truncation of voltage-dependent anion channel 1 is mediated by both asparagine endopeptidase and calpain 1 activities

The voltage-dependent anion channel 1 (VDAC1), an outer mitochondria membrane (OMM) protein, serves as a mitochondrial gatekeeper, mediating the transport of nucleotides, Ca(2+) and other metabolites across the OMM. VDAC1 also plays a central role in mitochondria-mediated apoptosis by facilitating t...

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Detalles Bibliográficos
Autores principales: Pahima, Hadas, Reina, Simona, Tadmor, Noa, Dadon-Klein, Daniella, Shteinfer-Kuzmine, Anna, Mazure, Nathalie M., De Pinto, Vito, Shoshan-Barmatz, Varda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849177/
https://www.ncbi.nlm.nih.gov/pubmed/29560113
http://dx.doi.org/10.18632/oncotarget.24377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849177/
https://www.ncbi.nlm.nih.gov/pubmed/29560113
http://dx.doi.org/10.18632/oncotarget.24377

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