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Hypoxic-induced truncation of voltage-dependent anion channel 1 is mediated by both asparagine endopeptidase and calpain 1 activities

The voltage-dependent anion channel 1 (VDAC1), an outer mitochondria membrane (OMM) protein, serves as a mitochondrial gatekeeper, mediating the transport of nucleotides, Ca(2+) and other metabolites across the OMM. VDAC1 also plays a central role in mitochondria-mediated apoptosis by facilitating t...

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Detalles Bibliográficos
Autores principales:	Pahima, Hadas, Reina, Simona, Tadmor, Noa, Dadon-Klein, Daniella, Shteinfer-Kuzmine, Anna, Mazure, Nathalie M., De Pinto, Vito, Shoshan-Barmatz, Varda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849177/ https://www.ncbi.nlm.nih.gov/pubmed/29560113 http://dx.doi.org/10.18632/oncotarget.24377

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