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Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing rate
OBJECTIVE: IGF-I is a growth factor, which is expressed in virtually all tissues. The circulating IGF-I is however derived mainly from the liver. IGF-I promotes wound healing and its levels are decreased in wounds with low regenerative potential such as diabetic wounds. However, the contribution of...
Autores principales: | Botusan, Ileana Ruxandra, Zheng, Xiaowei, Narayanan, Sampath, Grünler, Jacob, Sunkari, Vivekananda Gupta, Calissendorff, Freja S., Ansurudeen, Ishrath, Illies, Christopher, Svensson, Johan, Jansson, John-Olov, Ohlsson, Claes, Brismar, Kerstin, Catrina, Sergiu-Bogdan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849293/ https://www.ncbi.nlm.nih.gov/pubmed/29534073 http://dx.doi.org/10.1371/journal.pone.0193084 |
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