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DNA nanoparticles are safe and nontoxic in non-human primate eyes

INTRODUCTION: DNA nanoparticles (NPs) comprising polylysine conjugated to polyethylene glycol efficiently target murine photoreceptors and the retinal pigment epithelium (RPE) and lead to long-term phenotypic improvement in models of retinal degeneration. Advancing this technology requires testing i...

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Detalles Bibliográficos
Autores principales:	Kelley, Ryan A, Conley, Shannon M, Makkia, Rasha, Watson, Jamie N, Han, Zongchao, Cooper, Mark J, Naash, Muna I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849385/ https://www.ncbi.nlm.nih.gov/pubmed/29563793 http://dx.doi.org/10.2147/IJN.S157000

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