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Early structural and functional plasticity alterations in a susceptibility period of DYT1 dystonia mouse striatum
The onset of abnormal movements in DYT1 dystonia is between childhood and adolescence, although it is unclear why clinical manifestations appear during this developmental period. Plasticity at corticostriatal synapses is critically involved in motor memory. In the Tor1a(+/Δgag) DYT1 dystonia mouse m...
Autores principales: | Maltese, Marta, Stanic, Jennifer, Tassone, Annalisa, Sciamanna, Giuseppe, Ponterio, Giulia, Vanni, Valentina, Martella, Giuseppina, Imbriani, Paola, Bonsi, Paola, Mercuri, Nicola Biagio, Gardoni, Fabrizio, Pisani, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849413/ https://www.ncbi.nlm.nih.gov/pubmed/29504938 http://dx.doi.org/10.7554/eLife.33331 |
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