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Most bicarbonate secretion by Calu‐3 cells is mediated by CFTR and independent of pendrin

Bicarbonate plays an important role in airway host defense, however, its transport mechanisms remain uncertain. Here we examined the relative contributions of the anion channel CFTR (cystic fibrosis transmembrane conductance regulator, ABCC7) and the anion exchanger pendrin (SLC26A4) to HCO (3) (−)...

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Detalles Bibliográficos
Autores principales: Huang, Junwei, Kim, Dusik, Shan, Jiajie, Abu‐Arish, Asmahan, Luo, Yishan, Hanrahan, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849580/
https://www.ncbi.nlm.nih.gov/pubmed/29536650
http://dx.doi.org/10.14814/phy2.13641