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A novel C3d-containing oligomeric vaccine provides insight into the viability of testing human C3d-based vaccines in mice
The use of C3d, the final degradation product of complement protein C3, as a “natural” adjuvant has been widely examined since the initial documentation of its immunogenicity-enhancing properties as a consequence of binding to complement receptor 2. Subsequently it was demonstrated that these effect...
Autores principales: | He, Yong-Gang, Pappworth, Isabel Y., Rossbach, Andreas, Paulin, Joshua, Mavimba, Tarirai, Hayes, Christine, Kulik, Liudmila, Holers, V.Michael, Knight, Andrew M., Marchbank, Kevin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849677/ https://www.ncbi.nlm.nih.gov/pubmed/29017821 http://dx.doi.org/10.1016/j.imbio.2017.10.002 |
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