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Functionally distinct and selectively phosphorylated GPCR subpopulations co-exist in a single cell

G protein-coupled receptors (GPCRs) transduce pleiotropic intracellular signals in a broad range of physiological responses and disease states. Activated GPCRs can undergo agonist-induced phosphorylation by G protein receptor kinases (GRKs) and second messenger-dependent protein kinases such as prot...

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Detalles Bibliográficos
Autores principales:	Shen, Ao, Nieves-Cintron, Madeline, Deng, Yawen, Shi, Qian, Chowdhury, Dhrubajyoti, Qi, Jinyi, Hell, Johannes W., Navedo, Manuel F., Xiang, Yang K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849717/ https://www.ncbi.nlm.nih.gov/pubmed/29535304 http://dx.doi.org/10.1038/s41467-018-03459-7

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