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GATA3 zinc finger 2 mutations reprogram the breast cancer transcriptional network
GATA3 is frequently mutated in breast cancer; these mutations are widely presumed to be loss-of function despite a dearth of information regarding their effect on disease course or their mechanistic impact on the breast cancer transcriptional network. Here, we address molecular and clinical features...
Autores principales: | Takaku, Motoki, Grimm, Sara A., Roberts, John D., Chrysovergis, Kaliopi, Bennett, Brian D., Myers, Page, Perera, Lalith, Tucker, Charles J., Perou, Charles M., Wade, Paul A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849768/ https://www.ncbi.nlm.nih.gov/pubmed/29535312 http://dx.doi.org/10.1038/s41467-018-03478-4 |
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