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Single-use membrane adsorbers for endotoxin removal and purification of endogenous polysialic acid from Escherichia coli K1

Polysialic acid (polySia) is a promising molecule for various medical applications (e.g., treatment of inflammatory neurodegenerative diseases). In this study a complete production process for human-identical α-(2,8)-linked polySia was developed using a disposable bioreactor for cultivation of Esche...

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Detalles Bibliográficos
Autores principales:	de Vries, Ingo, Schreiber, Sarah, Boßmann, Daniel, Hellmann, Zawadi, Kopatz, Jens, Neumann, Harald, Beutel, Sascha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849784/ https://www.ncbi.nlm.nih.gov/pubmed/29541604 http://dx.doi.org/10.1016/j.btre.2018.02.001

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