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Cutting down the time to identify challenging tumor therapeutic targets and drug combinations using synthetic lethal approaches
Cancer drug discoverers and developers are blessed and cursed with a plethora of drug targets in the tumor cells themselves and the surrounding stromal elements. This bounty of targets has, at least in part, inspired the rapid increase in the number of clinically available small-molecule, biological...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000 Research Limited
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850089/ https://www.ncbi.nlm.nih.gov/pubmed/29568505 http://dx.doi.org/10.12688/f1000research.13679.1 |