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Impaired Cargo Clearance in the Retinal Pigment Epithelium (RPE) Underlies Irreversible Blinding Diseases

Chronic degeneration of the Retinal Pigment Epithelium (RPE) is a precursor to pathological changes in the outer retina. The RPE monolayer, which lies beneath the neuroretina, daily internalises and digests large volumes of spent photoreceptor outer segments. Impaired cargo handling and processing i...

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Detalles Bibliográficos
Autores principales:	Keeling, Eloise, Lotery, Andrew J., Tumbarello, David A., Ratnayaka, J. Arjuna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850104/ https://www.ncbi.nlm.nih.gov/pubmed/29473871 http://dx.doi.org/10.3390/cells7020016

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