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Proteinase-activated receptor 2 promotes tumor cell proliferation and metastasis by inducing epithelial-mesenchymal transition and predicts poor prognosis in hepatocellular carcinoma
AIM: To clarify the role of proteinase-activated receptor 2 (PAR2) in hepatocellular carcinoma, especially in the process of metastasis. METHODS: PAR2 expression levels were assessed by qRT-PCR and immunohistochemistry (IHC) in patient tissues and in hepatocellular carcinoma cell lines SMMC-7721 and...
Autores principales: | Sun, Liang, Li, Pi-Bao, Yao, Yan-Fen, Xiu, Ai-Yuan, Peng, Zhi, Bai, Yu-Huan, Gao, Yan-Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850131/ https://www.ncbi.nlm.nih.gov/pubmed/29563756 http://dx.doi.org/10.3748/wjg.v24.i10.1120 |
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