Adenosine Production by Biomaterial‐Supported Mesenchymal Stromal Cells Reduces the Innate Inflammatory Response in Myocardial Ischemia/Reperfusion Injury

BACKGROUND: During myocardial ischemia/reperfusion (MI/R) injury, there is extensive release of immunogenic metabolites that activate cells of the innate immune system. These include ATP and AMP, which upregulate chemotaxis, migration, and effector function of early infiltrating inflammatory cells....

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Eric Y., Wang, Lanfang, Zemskova, Marina, Deppen, Juline, Xu, Kai, Strobel, Frederick, García, Andrés J., Tirouvanziam, Rabindra, Levit, Rebecca D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850147/
https://www.ncbi.nlm.nih.gov/pubmed/29331956
http://dx.doi.org/10.1161/JAHA.117.006949

Ejemplares similares

Ejemplares similares