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Inhibition of 5‐Hydroxytryptamine Receptor 2B Reduced Vascular Restenosis and Mitigated the β‐Arrestin2–Mammalian Target of Rapamycin/p70S6K Pathway
BACKGROUND: As a monoamine neurotransmitter, 5‐hydroxytryptamine (5‐HT) or serotonin modulates mood, appetite, and sleep. Besides, 5‐HT also has important peripheral functions. 5‐HT receptor 2B (5‐HT2BR) plays a key role in cardiovascular diseases, such as pulmonary arterial hypertension and cardiac...
Autores principales: | Liu, Yahan, Wang, Zhipeng, Li, Jing, Ban, Yiqian, Mao, Guangmei, Zhang, Man, Wang, Mo, Liu, Yan, Zhao, Beilei, Shen, Qiang, Xu, Qingbo, Wang, Nanping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850233/ https://www.ncbi.nlm.nih.gov/pubmed/29382665 http://dx.doi.org/10.1161/JAHA.117.006810 |
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