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Breaking Symmetry in Viral Icosahedral Capsids as Seen through the Lenses of X-ray Crystallography and Cryo-Electron Microscopy

The majority of viruses on Earth form capsids built by multiple copies of one or more types of a coat protein arranged with 532 symmetry, generating an icosahedral shell. This highly repetitive structure is ideal to closely pack identical protein subunits and to enclose the nucleic acid genomes. How...

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Detalles Bibliográficos
Autores principales: Parent, Kristin N., Schrad, Jason R., Cingolani, Gino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850374/
https://www.ncbi.nlm.nih.gov/pubmed/29414851
http://dx.doi.org/10.3390/v10020067