Cargando…

Chondrocytes Contribute to Alphaviral Disease Pathogenesis as a Source of Virus Replication and Soluble Factor Production

Arthritogenic alphavirus infections often result in debilitating musculoskeletal disorders that affect the joints, muscle, and bone. In order to evaluate the infection profile of primary human skeletal muscle and chondrocyte cells to Ross River virus (RRV) in vitro, cells were infected at a multipli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lim, Elisa X. Y., Supramaniam, Aroon, Lui, Hayman, Coles, Peta, Lee, Wai Suet, Liu, Xiang, Rudd, Penny A., Herrero, Lara J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850393/ https://www.ncbi.nlm.nih.gov/pubmed/29462879 http://dx.doi.org/10.3390/v10020086

Ejemplares similares

De-Coding the Contributions of the Viral RNAs to Alphaviral Pathogenesis
por: LaPointe, Autumn T., et al.
Publicado: (2021)

Role of Pentraxin 3 in Shaping Arthritogenic Alphaviral Disease: From Enhanced Viral Replication to Immunomodulation
por: Foo, Suan-Sin, et al.
Publicado: (2015)

PG545 treatment reduces RRV-induced elevations of AST, ALT with secondary lymphoid organ alterations in C57BL/6 mice
por: Supramaniam, Aroon, et al.
Publicado: (2019)

Pathways Activated by Infected and Bystander Chondrocytes in Response to Ross River Virus Infection
por: Lim, Elisa X. Y., et al.
Publicado: (2022)

P12-15. Replication enhancement of an alphaviral-lentiviral replicating chimeric particle (RCP) vaccine
por: Young, K, et al.
Publicado: (2009)

Correction: Role of Pentraxin 3 in Shaping Arthritogenic Alphaviral Disease: From Enhanced Viral Replication to Immunomodulation
Publicado: (2015)

Anti-Alphaviral Alkaloids: Focus on Some Isoquinolines, Indoles and Quinolizidines
por: Sandenon Seteyen, Anne-Laure, et al.
Publicado: (2022)

311. Heterologous immunity and host susceptibility to emerging alphaviral infections
por: Vittor, Amy Y, et al.
Publicado: (2023)

Role of innate signalling pathways in the immunogenicity of alphaviral replicon-based vaccines
por: Näslund, Tanja I, et al.
Publicado: (2011)

The Alphaviral Capsid Protein Inhibits IRAK1-Dependent TLR Signaling
por: Landers, V. Douglas, et al.
Publicado: (2021)

Lower temperatures reduce type I interferon activity and promote alphaviral arthritis
por: Prow, Natalie A., et al.
Publicado: (2017)

Comparative analyses of alphaviral RNA:Protein complexes reveals conserved host-pathogen interactions
por: Gebhart, Natasha N., et al.
Publicado: (2020)

Arthritogenic Alphavirus-Induced Immunopathology and Targeting Host Inflammation as A Therapeutic Strategy for Alphaviral Disease
por: Mostafavi, Helen, et al.
Publicado: (2019)

Mosquitoes as Suitable Vectors for Alphaviruses
por: Lim, Elisa X. Y., et al.
Publicado: (2018)

High efficiency of alphaviral gene transfer in combination with 5-fluorouracil in a mouse mammary tumor model
por: Zajakina, Anna, et al.
Publicado: (2014)

Dancing with the Devil: A Review of the Importance of Host RNA-Binding Proteins to Alphaviral RNAs during Infection
por: Westcott, Claire E., et al.
Publicado: (2023)

Bioluminescent Ross River Virus Allows Live Monitoring of Acute and Long-Term Alphaviral Infection by In Vivo Imaging
por: Belarbi, Essia, et al.
Publicado: (2019)

Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis
por: Hwang, Hyun Sook, et al.
Publicado: (2015)

The Roles of Ebola Virus Soluble Glycoprotein in Replication, Pathogenesis, and Countermeasure Development
por: Zhu, Wenjun, et al.
Publicado: (2019)

Pentosan polysulfate sodium prevents functional decline in chikungunya infected mice by modulating growth factor signalling and lymphocyte activation
por: Rudd, Penny A., et al.
Publicado: (2021)

T cell–chondrocyte interaction in the pathogenesis of osteoarthritis
por: Nakamura, H, et al.
Publicado: (2003)

Phase I study of alphaviral vector (AVX701) in colorectal cancer patients: comparison of immune responses in stage III and stage IV patients
por: Morse, Michael A, et al.
Publicado: (2015)

The First Human Epitope Map of the Alphaviral E1 and E2 Proteins Reveals a New E2 Epitope with Significant Virus Neutralizing Activity
por: Hunt, Ann R., et al.
Publicado: (2010)

Antigenic and immunogenic properties of chondrocytes. Implications for chondrocyte therapeutic transplantation and pathogenesis of inflammatory and degenerative joint diseases
por: Osiecka-Iwan, Anna, et al.
Publicado: (2018)

Transcriptomic changes during the replicative senescence of human articular chondrocytes
por: Atasoy-Zeybek, Aysegul, et al.
Publicado: (2023)

Increased 15-lipoxygenase-1 expression in chondrocytes contributes to the pathogenesis of osteoarthritis
por: Chen, Kaizhe, et al.
Publicado: (2017)

Pathogenesis of Osteoarthritis: Risk Factors, Regulatory Pathways in Chondrocytes, and Experimental Models
por: He, Yuchen, et al.
Publicado: (2020)

Autophagy in viral replication and pathogenesis
por: Sir, Donna, et al.
Publicado: (2010)

Coronaviruses: An Overview of Their Replication and Pathogenesis
por: Fehr, Anthony R., et al.
Publicado: (2015)

Mosquito antiviral defense mechanisms: a delicate balance between innate immunity and persistent viral infection
por: Lee, Wai-Suet, et al.
Publicado: (2019)

CircGNB1 drives osteoarthritis pathogenesis by inducing oxidative stress in chondrocytes
por: Liang, Yi, et al.
Publicado: (2023)

Efficiency of Human Epiphyseal Chondrocytes with Differential Replication Numbers for Cellular Therapy Products
por: Nasu, Michiyo, et al.
Publicado: (2016)

Junín Virus Pathogenesis and Virus Replication
por: Grant, Ashley, et al.
Publicado: (2012)

Annexins in Influenza Virus Replication and Pathogenesis
por: Ampomah, Patrick Baah, et al.
Publicado: (2018)

CD8(+) T cells implicated in the pathogenesis of allergic fungal rhinosinusitis
por: Pant, Harshita, et al.
Publicado: (2014)

Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis
por: Yang, Run-Ze, et al.
Publicado: (2021)

Apoptosis Activation and Autophagy Inhibition of Chondrocytes by Leptin by the Upregulation of LOXL3 in Osteoarthritis Pathogenesis
por: Wei, Qianhao
Publicado: (2022)

Editorial of Special Issue “Genetics and Molecular Pathogenesis of Non-Ischemic Cardiomyopathies”
por: Lombardi, Raffaella, et al.
Publicado: (2020)

Coronaviruses post-SARS: update on replication and pathogenesis
por: Perlman, Stanley, et al.
Publicado: (2009)

Pleiotropic roles of metallothioneins as regulators of chondrocyte apoptosis and catabolic and anabolic pathways during osteoarthritis pathogenesis
por: Won, Yoonkyung, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_2u65qvf47dan70fjh0hmn8oqjf