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Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus

A 2-year-old boy with highly pathogenic avian influenza A(H5N1) virus infection with minimal respiratory symptoms developed encephalitis complicated by obstructive hydrocephalus. Viral RNA was detectable in cerebrospinal fluid. The virus belonged to H5N1 clade 2.3.2.1b and had acquired the mammalian...

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Autores principales: Mak, Gannon Chun Kit, Kwan, Mike Yat-wah, Mok, Chris Ka Pun, Lo, Janice Yee Chi, Peiris, Malik, Leung, Chi Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850530/
https://www.ncbi.nlm.nih.gov/pubmed/29020163
http://dx.doi.org/10.1093/cid/cix707
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author Mak, Gannon Chun Kit
Kwan, Mike Yat-wah
Mok, Chris Ka Pun
Lo, Janice Yee Chi
Peiris, Malik
Leung, Chi Wai
author_facet Mak, Gannon Chun Kit
Kwan, Mike Yat-wah
Mok, Chris Ka Pun
Lo, Janice Yee Chi
Peiris, Malik
Leung, Chi Wai
author_sort Mak, Gannon Chun Kit
collection PubMed
description A 2-year-old boy with highly pathogenic avian influenza A(H5N1) virus infection with minimal respiratory symptoms developed encephalitis complicated by obstructive hydrocephalus. Viral RNA was detectable in cerebrospinal fluid. The virus belonged to H5N1 clade 2.3.2.1b and had acquired the mammalian adaptation mutation PB2 Q591K.
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spelling pubmed-58505302018-03-23 Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus Mak, Gannon Chun Kit Kwan, Mike Yat-wah Mok, Chris Ka Pun Lo, Janice Yee Chi Peiris, Malik Leung, Chi Wai Clin Infect Dis Brief Reports A 2-year-old boy with highly pathogenic avian influenza A(H5N1) virus infection with minimal respiratory symptoms developed encephalitis complicated by obstructive hydrocephalus. Viral RNA was detectable in cerebrospinal fluid. The virus belonged to H5N1 clade 2.3.2.1b and had acquired the mammalian adaptation mutation PB2 Q591K. Oxford University Press 2018-01-01 2017-08-07 /pmc/articles/PMC5850530/ /pubmed/29020163 http://dx.doi.org/10.1093/cid/cix707 Text en © The Author(s) 2017. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Reports
Mak, Gannon Chun Kit
Kwan, Mike Yat-wah
Mok, Chris Ka Pun
Lo, Janice Yee Chi
Peiris, Malik
Leung, Chi Wai
Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus
title Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus
title_full Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus
title_fullStr Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus
title_full_unstemmed Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus
title_short Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus
title_sort influenza a(h5n1) virus infection in a child with encephalitis complicated by obstructive hydrocephalus
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850530/
https://www.ncbi.nlm.nih.gov/pubmed/29020163
http://dx.doi.org/10.1093/cid/cix707
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