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A rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child

We are reporting a rare case of hemolytic disease of newborn with weak D antigen in child. A 3(rd) order male child of G(3)P(3)A(0) mother was admitted at 8(th) h of life with jaundice. Blood group of both mother and child were A Rh D negative. Baby's direct coombs test was positive. Weak D ant...

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Autores principales: Dava, Nirav Ramesh, Upadhyaya, Alok, Agarwal, Neha, Mehta, Amarjeet, Choudhary, Vijaypal, Goyal, Gourav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850702/
https://www.ncbi.nlm.nih.gov/pubmed/29563680
http://dx.doi.org/10.4103/ajts.AJTS_21_17
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author Dava, Nirav Ramesh
Upadhyaya, Alok
Agarwal, Neha
Mehta, Amarjeet
Choudhary, Vijaypal
Goyal, Gourav
author_facet Dava, Nirav Ramesh
Upadhyaya, Alok
Agarwal, Neha
Mehta, Amarjeet
Choudhary, Vijaypal
Goyal, Gourav
author_sort Dava, Nirav Ramesh
collection PubMed
description We are reporting a rare case of hemolytic disease of newborn with weak D antigen in child. A 3(rd) order male child of G(3)P(3)A(0) mother was admitted at 8(th) h of life with jaundice. Blood group of both mother and child were A Rh D negative. Baby's direct coombs test was positive. Weak D antigen was positive in baby. Hematological parameters showed all the signs of ongoing hemolysis, and the bilirubin level was in the zone of exchange transfusion. Exchange transfusion was done. An intravenous immunoglobulin was given to child after that. Mother had a history of first normal healthy male child with O Rh D positive blood group. Second male child expired on 3(rd) postnatal day due to bilirubin encephalopathy that had A Rh D negative blood group with positive direct coombs test.
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spelling pubmed-58507022018-03-21 A rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child Dava, Nirav Ramesh Upadhyaya, Alok Agarwal, Neha Mehta, Amarjeet Choudhary, Vijaypal Goyal, Gourav Asian J Transfus Sci Case Report We are reporting a rare case of hemolytic disease of newborn with weak D antigen in child. A 3(rd) order male child of G(3)P(3)A(0) mother was admitted at 8(th) h of life with jaundice. Blood group of both mother and child were A Rh D negative. Baby's direct coombs test was positive. Weak D antigen was positive in baby. Hematological parameters showed all the signs of ongoing hemolysis, and the bilirubin level was in the zone of exchange transfusion. Exchange transfusion was done. An intravenous immunoglobulin was given to child after that. Mother had a history of first normal healthy male child with O Rh D positive blood group. Second male child expired on 3(rd) postnatal day due to bilirubin encephalopathy that had A Rh D negative blood group with positive direct coombs test. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5850702/ /pubmed/29563680 http://dx.doi.org/10.4103/ajts.AJTS_21_17 Text en Copyright: © 2018 Asian Journal of Transfusion Science http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Dava, Nirav Ramesh
Upadhyaya, Alok
Agarwal, Neha
Mehta, Amarjeet
Choudhary, Vijaypal
Goyal, Gourav
A rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child
title A rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child
title_full A rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child
title_fullStr A rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child
title_full_unstemmed A rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child
title_short A rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child
title_sort rare case of hemolytic disease of newborn due to weak d (d unknown) antigen in child
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850702/
https://www.ncbi.nlm.nih.gov/pubmed/29563680
http://dx.doi.org/10.4103/ajts.AJTS_21_17
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