Anti Kp(a) alloantibody: Development of a rare alloantibody in a non-Hodgkin's lymphoma patient of Indian origin

The Kell blood group system is complex, contains many antigens, highly immunogenic, and potent in triggering immune reactions. Antibodies to Kell blood group system are the most common immune red cell antibodies, following ABO and Rh. However, among the anti-Kell antibodies; anti-Kp(a) is extremely...

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Detalles Bibliográficos
Autores principales: Mangwana, Sadhana, Gangwar, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850705/
https://www.ncbi.nlm.nih.gov/pubmed/29563682
http://dx.doi.org/10.4103/ajts.AJTS_23_17
Descripción
Sumario:The Kell blood group system is complex, contains many antigens, highly immunogenic, and potent in triggering immune reactions. Antibodies to Kell blood group system are the most common immune red cell antibodies, following ABO and Rh. However, among the anti-Kell antibodies; anti-Kp(a) is extremely rare. We report an interesting case of Anti-Kp(a) in a 59-year-old female patient of Non-Hodgkin's Lymphoma, post radiotherapy, who first developed warm autoantibody and later developed anti-Kp(a) alloantibody on multiple transfusions.

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