Anti Kp(a) alloantibody: Development of a rare alloantibody in a non-Hodgkin's lymphoma patient of Indian origin

The Kell blood group system is complex, contains many antigens, highly immunogenic, and potent in triggering immune reactions. Antibodies to Kell blood group system are the most common immune red cell antibodies, following ABO and Rh. However, among the anti-Kell antibodies; anti-Kp(a) is extremely...

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Autores principales: Mangwana, Sadhana, Gangwar, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850705/
https://www.ncbi.nlm.nih.gov/pubmed/29563682
http://dx.doi.org/10.4103/ajts.AJTS_23_17
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author Mangwana, Sadhana
Gangwar, Vivek
author_facet Mangwana, Sadhana
Gangwar, Vivek
author_sort Mangwana, Sadhana
collection PubMed
description The Kell blood group system is complex, contains many antigens, highly immunogenic, and potent in triggering immune reactions. Antibodies to Kell blood group system are the most common immune red cell antibodies, following ABO and Rh. However, among the anti-Kell antibodies; anti-Kp(a) is extremely rare. We report an interesting case of Anti-Kp(a) in a 59-year-old female patient of Non-Hodgkin's Lymphoma, post radiotherapy, who first developed warm autoantibody and later developed anti-Kp(a) alloantibody on multiple transfusions.
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spelling pubmed-58507052018-03-21 Anti Kp(a) alloantibody: Development of a rare alloantibody in a non-Hodgkin's lymphoma patient of Indian origin Mangwana, Sadhana Gangwar, Vivek Asian J Transfus Sci Case Report The Kell blood group system is complex, contains many antigens, highly immunogenic, and potent in triggering immune reactions. Antibodies to Kell blood group system are the most common immune red cell antibodies, following ABO and Rh. However, among the anti-Kell antibodies; anti-Kp(a) is extremely rare. We report an interesting case of Anti-Kp(a) in a 59-year-old female patient of Non-Hodgkin's Lymphoma, post radiotherapy, who first developed warm autoantibody and later developed anti-Kp(a) alloantibody on multiple transfusions. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5850705/ /pubmed/29563682 http://dx.doi.org/10.4103/ajts.AJTS_23_17 Text en Copyright: © 2018 Asian Journal of Transfusion Science http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Mangwana, Sadhana
Gangwar, Vivek
Anti Kp(a) alloantibody: Development of a rare alloantibody in a non-Hodgkin's lymphoma patient of Indian origin
title Anti Kp(a) alloantibody: Development of a rare alloantibody in a non-Hodgkin's lymphoma patient of Indian origin
title_full Anti Kp(a) alloantibody: Development of a rare alloantibody in a non-Hodgkin's lymphoma patient of Indian origin
title_fullStr Anti Kp(a) alloantibody: Development of a rare alloantibody in a non-Hodgkin's lymphoma patient of Indian origin
title_full_unstemmed Anti Kp(a) alloantibody: Development of a rare alloantibody in a non-Hodgkin's lymphoma patient of Indian origin
title_short Anti Kp(a) alloantibody: Development of a rare alloantibody in a non-Hodgkin's lymphoma patient of Indian origin
title_sort anti kp(a) alloantibody: development of a rare alloantibody in a non-hodgkin's lymphoma patient of indian origin
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850705/
https://www.ncbi.nlm.nih.gov/pubmed/29563682
http://dx.doi.org/10.4103/ajts.AJTS_23_17
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AT gangwarvivek antikpaalloantibodydevelopmentofararealloantibodyinanonhodgkinslymphomapatientofindianorigin

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