Suspected Artesunate Resistant Malaria in South India

We report four cases of complicated malaria in Andhra Pradesh-Orissa border between July 2016 and December 2016, with apparent treatment failure with artemisinin drugs, and all showing parasitological clearance after quinine and adjuvant clindamycin therapy. However, one case died due to complicatio...

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Autores principales: Akunuri, Shalini, Shraddha, Pandey, Palli, Vedita, MuraliSantosh, Buddha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850760/
https://www.ncbi.nlm.nih.gov/pubmed/29563721
http://dx.doi.org/10.4103/jgid.jgid_180_16
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author Akunuri, Shalini
Shraddha, Pandey
Palli, Vedita
MuraliSantosh, Buddha
author_facet Akunuri, Shalini
Shraddha, Pandey
Palli, Vedita
MuraliSantosh, Buddha
author_sort Akunuri, Shalini
collection PubMed
description We report four cases of complicated malaria in Andhra Pradesh-Orissa border between July 2016 and December 2016, with apparent treatment failure with artemisinin drugs, and all showing parasitological clearance after quinine and adjuvant clindamycin therapy. However, one case died due to complications of malaria. We highlight the need for increased monitoring and surveillance to identify artemisinin combination therapy resistance in other parts of India apart from Northeastern states. It is also essential to ensure rationale use of the existing antimalarial drugs.
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spelling pubmed-58507602018-03-21 Suspected Artesunate Resistant Malaria in South India Akunuri, Shalini Shraddha, Pandey Palli, Vedita MuraliSantosh, Buddha J Glob Infect Dis Case Report We report four cases of complicated malaria in Andhra Pradesh-Orissa border between July 2016 and December 2016, with apparent treatment failure with artemisinin drugs, and all showing parasitological clearance after quinine and adjuvant clindamycin therapy. However, one case died due to complications of malaria. We highlight the need for increased monitoring and surveillance to identify artemisinin combination therapy resistance in other parts of India apart from Northeastern states. It is also essential to ensure rationale use of the existing antimalarial drugs. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5850760/ /pubmed/29563721 http://dx.doi.org/10.4103/jgid.jgid_180_16 Text en Copyright: © 2018 Journal of Global Infectious Diseases http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Akunuri, Shalini
Shraddha, Pandey
Palli, Vedita
MuraliSantosh, Buddha
Suspected Artesunate Resistant Malaria in South India
title Suspected Artesunate Resistant Malaria in South India
title_full Suspected Artesunate Resistant Malaria in South India
title_fullStr Suspected Artesunate Resistant Malaria in South India
title_full_unstemmed Suspected Artesunate Resistant Malaria in South India
title_short Suspected Artesunate Resistant Malaria in South India
title_sort suspected artesunate resistant malaria in south india
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850760/
https://www.ncbi.nlm.nih.gov/pubmed/29563721
http://dx.doi.org/10.4103/jgid.jgid_180_16
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AT shraddhapandey suspectedartesunateresistantmalariainsouthindia
AT pallivedita suspectedartesunateresistantmalariainsouthindia
AT muralisantoshbuddha suspectedartesunateresistantmalariainsouthindia

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