A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials

The concept of regulatory T cell (Treg)-based immunotherapy has enormous potential for facilitating tolerance in autoimmunity and transplantation. Clinical translation of Treg cell therapy requires production processes that satisfy the rigors of Good Manufacturing Practice (GMP) standards. In this r...

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Detalles Bibliográficos
Autores principales: Fraser, Henrieta, Safinia, Niloufar, Grageda, Nathali, Thirkell, Sarah, Lowe, Katie, Fry, Laura J., Scottá, Cristiano, Hope, Andrew, Fisher, Christopher, Hilton, Rachel, Game, David, Harden, Paul, Bushell, Andrew, Wood, Kathryn, Lechler, Robert I., Lombardi, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850906/
https://www.ncbi.nlm.nih.gov/pubmed/29552576
http://dx.doi.org/10.1016/j.omtm.2018.01.006

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