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Absence of synemin in mice causes structural and functional abnormalities in heart

Cardiomyopathies have been linked to changes in structural proteins, including intermediate filament (IF) proteins located in the cytoskeleton. IFs associate with the contractile machinery and costameres of striated muscle and with intercalated disks in the heart. Synemin is a large IF protein that...

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Detalles Bibliográficos
Autores principales: García-Pelagio, Karla P., Chen, Ling, Joca, Humberto C., Ward, Christopher, Lederer, W. Jonathan, Bloch, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850968/
https://www.ncbi.nlm.nih.gov/pubmed/29247678
http://dx.doi.org/10.1016/j.yjmcc.2017.12.005