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No evidence for association of MTHFR 677C>T and 1298A>C variants with placental DNA methylation

BACKGROUND: 5,10-Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in one-carbon metabolism that ensures the availability of methyl groups for methylation reactions. Two single-nucleotide polymorphisms (SNPs) in the MTHFR gene, 677C>T and 1298A>C, result in a thermolabile enzyme with...

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Detalles Bibliográficos
Autores principales:	Del Gobbo, Giulia F., Price, E. Magda, Hanna, Courtney W., Robinson, Wendy P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851070/ https://www.ncbi.nlm.nih.gov/pubmed/29564022 http://dx.doi.org/10.1186/s13148-018-0468-1

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