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Elevated whole muscle phosphatidylcholine: phosphatidylethanolamine ratio coincides with reduced SERCA activity in murine overloaded plantaris muscles
BACKGROUND: An increase in phosphatidylcholine:phosphatidylethanolamine (PC:PE) and a decrease in fatty acyl chain length, monounsaturated:polyunsaturated (MUFA:PUFA) fatty acyl ratio reduces SERCA activity in liposomes and in mouse models of obesity and muscular dystrophy. We have previously shown...
Autores principales: | Fajardo, Val A., Mikhaeil, John S., Leveille, Cameron F., Tupling, A. Russell, LeBlanc, Paul J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851149/ https://www.ncbi.nlm.nih.gov/pubmed/29534725 http://dx.doi.org/10.1186/s12944-018-0687-7 |
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