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Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: cohort studies and meta-analyses of 362,338 individuals

BACKGROUND: Clusterin, also known as apolipoprotein J (apoJ), is one of the most abundantly expressed apolipoproteins in the brain after apolipoprotein E (apoE). Like the ε4 allele of the apolipoprotein E gene (APOE), the clusterin gene (CLU) is a risk locus for Alzheimer’s disease, and may play add...

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Detalles Bibliográficos
Autores principales:	Nordestgaard, Liv Tybjærg, Tybjærg-Hansen, Anne, Rasmussen, Katrine Laura, Nordestgaard, Børge G., Frikke-Schmidt, Ruth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851250/ https://www.ncbi.nlm.nih.gov/pubmed/29534716 http://dx.doi.org/10.1186/s12916-018-1029-3

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