Immediate effects of exercise intervention on cancer-related fatigue

[Purpose] To verify the immediate effects of exercise therapy on cancer-related fatigue (CRF) in cancer patients. [Subjects and Methods] Eighteen cancer patients who performed exercise therapy targeting a rating of 4 (somewhat strong) on the Borg category-ratio scale (CR-10) were enrolled. CRF was evaluated using the Cancer Fatigue Scale (CFS). CFS was evaluated in clinical practice immediately before and after exercise therapy on the 1st or 2nd day of physiotherapy for CRF management. CFS scores before and after exercise were compared to determine how CRF changed due to exercise therapy. [Results] CFS physical, CFS affective, CFS cognitive, and CFS total all decreased following exercise therapy, and the changes in CFS physical and CFS total were statistically significant. The effect sizes for CFS physical and CFS total were “medium”, and for CFS affective and CFS cognitive “small.” [Conclusion] These findings suggest that exercise therapy targeting a rating of 4 (somewhat strong) on the CR-10 can immediately reduce CRF in cancer patients.