Measuring Integrin Conformational Change on the Cell Surface with Super-Resolution Microscopy

We use super-resolution interferometric photoactivation and localization microscopy (iPALM) and a constrained photoactivatable fluorescent protein integrin fusion to measure the displacement of the head of integrin lymphocyte function-associated 1 (LFA-1) resulting from integrin conformational chang...

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Detalles Bibliográficos
Autores principales: Moore, Travis I., Aaron, Jesse, Chew, Teng-Leong, Springer, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851489/
https://www.ncbi.nlm.nih.gov/pubmed/29444440
http://dx.doi.org/10.1016/j.celrep.2018.01.062

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